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Set up of a protocol for rat plasma peptidomics in hemorrhagic shock model in presence of heparin
A preliminary mass spectrometry based shotgun protocol was set up to compare the peptidome of plasma samples from healthy and hemorrhagic shock rats with the aim of verifying the possible role of uncontrolled proteolytic activity in circulatory shock. Since the hemorrhagic shock model requires hepar...
Autores principales: | Maffioli, Elisa, Aletti, Federico, Santagata, Fabiana, Negri, Armando, Santamaria, Marco H., De Lano, Frank A., Kistler, Erik B., Schmid-Schönbein, Geert W., Tedeschi, Gabriella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988501/ https://www.ncbi.nlm.nih.gov/pubmed/29900112 http://dx.doi.org/10.1016/j.euprot.2016.03.004 |
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