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Experimental setup for the identification of mitochondrial protease substrates by shotgun and top-down proteomics
Mitochondria possess a proteolytic system that contributes to the regulation of mitochondrial dynamics, mitochondrial biogenesis and mitophagy. We aimed at the identification by bottom-up proteomics of altered protein processing due to the activation of mitochondrial proteases in a cellular model of...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988556/ https://www.ncbi.nlm.nih.gov/pubmed/29900104 http://dx.doi.org/10.1016/j.euprot.2016.02.002 |