Experimental setup for the identification of mitochondrial protease substrates by shotgun and top-down proteomics

Mitochondria possess a proteolytic system that contributes to the regulation of mitochondrial dynamics, mitochondrial biogenesis and mitophagy. We aimed at the identification by bottom-up proteomics of altered protein processing due to the activation of mitochondrial proteases in a cellular model of...

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Detalles Bibliográficos
Autores principales: Di Pierro, Alice, Bondi, Heather, Monti, Chiara, Pieroni, Luisa, Cilio, Enrico, Urbani, Andrea, Alberio, Tiziana, Fasano, Mauro, Ronci, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Special Section: Proceedings of the 9th Annual EuPA Congress “Proteomics - Back to the Future” (June 23 - 28, 2015, Milano, Italy)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988556/
https://www.ncbi.nlm.nih.gov/pubmed/29900104
http://dx.doi.org/10.1016/j.euprot.2016.02.002

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