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Insulin receptor substrate 2: a bridge between Hippo and AKT pathways

NAFLD induces the development of advanced liver diseases such as NASH and liver cancer. Therefore, understanding the mechanism of NAFLD development is critical for its prevention and treatment. Ablation of PTEN or Hippo pathway components induces liver cancer in a murine model by hyperactive AKT or...

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Detalles Bibliográficos
Autores principales: Jeong, Sun-Hye, Lim, Dae-Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988573/
https://www.ncbi.nlm.nih.gov/pubmed/29699606
http://dx.doi.org/10.5483/BMBRep.2018.51.5.095