Cargando…
Insulin receptor substrate 2: a bridge between Hippo and AKT pathways
NAFLD induces the development of advanced liver diseases such as NASH and liver cancer. Therefore, understanding the mechanism of NAFLD development is critical for its prevention and treatment. Ablation of PTEN or Hippo pathway components induces liver cancer in a murine model by hyperactive AKT or...
Autores principales: | Jeong, Sun-Hye, Lim, Dae-Sik |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988573/ https://www.ncbi.nlm.nih.gov/pubmed/29699606 http://dx.doi.org/10.5483/BMBRep.2018.51.5.095 |
Ejemplares similares
-
The Hippo/YAP signaling pathway: the driver of cancer metastasis
por: Zhou, Tianxing, et al.
Publicado: (2023) -
Role of the STRIPAK complex and the Hippo pathway in synaptic terminal formation
por: Sakuma, Chisako, et al.
Publicado: (2017) -
Dishevelling Wnt and Hippo
por: Kim, Nam Hee, et al.
Publicado: (2018) -
RBL2/p130: a direct AKT substrate and mediator of AKT inhibition-induced apoptosis
por: Ventura, Elisa, et al.
Publicado: (2018) -
Hippo signaling: bridging the gap between cancer and neurodegenerative disorders
por: Gogia, Neha, et al.
Publicado: (2020)