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Inhibition of Wntless/GPR177 suppresses gastric tumorigenesis

Wntless/GPR177 functions as WNT ligand carrier protein and activator of WNT/β-catenin signaling, however, its molecular role in gastric cancer (GC) has remained elusive. We investigated the role of GPR177 in gastric tumorigenesis and provided the therapeutic potential of a clinical development of an...

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Detalles Bibliográficos
Autores principales: Seo, Jaesung, Kee, Hyun Jung, Choi, Hye Ji, Lee, Jae Eun, Park, Soo-Yeon, Lee, Seung-Hyun, Jeong, Mi-Hyeon, Guk, Garam, Lee, SooYeon, Choi, Kyung-Chul, Choi, Yoon Young, Kim, Hyunki, Noh, Sung Hoon, Yoon, Ho-Geun, Cheong, Jae-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988581/
https://www.ncbi.nlm.nih.gov/pubmed/29555015
http://dx.doi.org/10.5483/BMBRep.2018.51.5.046