An ERK-Dependent Feedback Mechanism Prevents Hematopoietic Stem Cell Exhaustion

Hematopoietic stem cells (HSCs) sustain hematopoiesis throughout life. HSCs exit dormancy to restore hemostasis in response to stressful events, such as acute blood loss, and must return to a quiescent state to prevent their exhaustion and resulting bone marrow failure. HSC activation is driven in p...

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Detalles Bibliográficos
Autores principales: Baumgartner, Christian, Toifl, Stefanie, Farlik, Matthias, Halbritter, Florian, Scheicher, Ruth, Fischer, Irmgard, Sexl, Veronika, Bock, Christoph, Baccarini, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988582/
https://www.ncbi.nlm.nih.gov/pubmed/29804890
http://dx.doi.org/10.1016/j.stem.2018.05.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988582/
https://www.ncbi.nlm.nih.gov/pubmed/29804890
http://dx.doi.org/10.1016/j.stem.2018.05.003

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