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Mild Therapeutic Hypothermia Protects the Brain from Ischemia/Reperfusion Injury through Upregulation of iASPP

Mild therapeutic hypothermia, a robust neuroprotectant, reduces neuronal apoptosis, but the precise mechanism is not well understood. Our previous study showed that a novel inhibitor of an apoptosis-stimulating protein of p53 (iASPP) might be involved in neuronal death after stroke. The aim of this...

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Detalles Bibliográficos
Autores principales: Liu, Xiangrong, Wen, Shaohong, Zhao, Shunying, Yan, Feng, Zhao, Shangfeng, Wu, Di, Ji, Xunming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988595/
https://www.ncbi.nlm.nih.gov/pubmed/29896428
http://dx.doi.org/10.14336/AD.2017.0703