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BDNF Polymorphism: A Review of Its Diagnostic and Clinical Relevance in Neurodegenerative Disorders

Brain-derived neurotrophic factor (BDNF) has a unique role in the neuronal development, differentiation, and survival in the developing and adult nervous system. A common single-nucleotide polymorphism in the pro-region of the human BDNF gene, resulting in a valine to methionine substitution (Val66M...

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Detalles Bibliográficos
Autores principales: Shen, Ting, You, Yuyi, Joseph, Chitra, Mirzaei, Mehdi, Klistorner, Alexander, Graham, Stuart L., Gupta, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988606/
https://www.ncbi.nlm.nih.gov/pubmed/29896439
http://dx.doi.org/10.14336/AD.2017.0717