Adjuvant composition and delivery route shape immune response quality and protective efficacy of a recombinant vaccine for Entamoeba histolytica

Amebiasis caused by Entamoeba histolytica is the third leading cause of parasitic mortality globally, with some 100,000 deaths annually, primarily among young children. Protective immunity to amebiasis is associated with fecal IgA and IFN-γ in humans; however, no vaccine exists. We have previously i...

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Detalles Bibliográficos
Autores principales: Abhyankar, Mayuresh M., Orr, Mark T., Lin, Susan, Suraju, Mohammed O., Simpson, Adrian, Blust, Molly, Pham, Tiep, Guderian, Jeffrey A., Tomai, Mark A., Elvecrog, James, Pedersen, Karl, Petri, William A., Fox, Christopher B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988657/
https://www.ncbi.nlm.nih.gov/pubmed/29900011
http://dx.doi.org/10.1038/s41541-018-0060-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988657/
https://www.ncbi.nlm.nih.gov/pubmed/29900011
http://dx.doi.org/10.1038/s41541-018-0060-x

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