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Intravascular haemolysis in severe Plasmodium knowlesi malaria: association with endothelial activation, microvascular dysfunction, and acute kidney injury

Plasmodium knowlesi occurs throughout Southeast Asia, and is the most common cause of human malaria in Malaysia. Severe disease in humans is characterised by high parasite biomass, reduced red blood cell deformability, endothelial activation and microvascular dysfunction. However, the roles of intra...

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Detalles Bibliográficos
Autores principales: Barber, Bridget E., Grigg, Matthew J., Piera, Kim A., William, Timothy, Cooper, Daniel J., Plewes, Katherine, Dondorp, Arjen M., Yeo, Tsin W., Anstey, Nicholas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988665/
https://www.ncbi.nlm.nih.gov/pubmed/29872039
http://dx.doi.org/10.1038/s41426-018-0105-2