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The homeobox protein VentX reverts immune suppression in the tumor microenvironment

Immune suppression in the tumor microenvironment (TME) is a central obstacle to effective immunotherapy. Tumor-associated macrophages (TAMs) are key components of the TME. Although TAMs have been viewed as an ideal target of intervention to steer immunity in cancer treatment, the approach has been h...

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Detalles Bibliográficos
Autores principales: Le, Yi, Gao, Hong, Bleday, Ronald, Zhu, Zhenglun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988690/
https://www.ncbi.nlm.nih.gov/pubmed/29872044
http://dx.doi.org/10.1038/s41467-018-04567-0