Dual roles of TRF1 in tethering telomeres to the nuclear envelope and protecting them from fusion during meiosis

Telomeres integrity is indispensable for chromosomal stability by preventing chromosome erosion and end-to-end fusions. During meiosis, telomeres attach to the inner nuclear envelope and cluster into a highly crowded microenvironment at the bouquet stage, which requires specific mechanisms to protec...

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Detalles Bibliográficos
Autores principales: Wang, Lina, Tu, Zhaowei, Liu, Chao, Liu, Hongbin, Kaldis, Philipp, Chen, Zijiang, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988695/
https://www.ncbi.nlm.nih.gov/pubmed/29311622
http://dx.doi.org/10.1038/s41418-017-0037-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988695/
https://www.ncbi.nlm.nih.gov/pubmed/29311622
http://dx.doi.org/10.1038/s41418-017-0037-8

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