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Dual roles of TRF1 in tethering telomeres to the nuclear envelope and protecting them from fusion during meiosis
Telomeres integrity is indispensable for chromosomal stability by preventing chromosome erosion and end-to-end fusions. During meiosis, telomeres attach to the inner nuclear envelope and cluster into a highly crowded microenvironment at the bouquet stage, which requires specific mechanisms to protec...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988695/ https://www.ncbi.nlm.nih.gov/pubmed/29311622 http://dx.doi.org/10.1038/s41418-017-0037-8 |