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Prestressed cells are prone to cytoskeleton failures under localized shear strain: an experimental demonstration on muscle precursor cells

We report on a wavelet based space-scale decomposition method for analyzing the response of living muscle precursor cells (C2C12 myoblasts and myotubes) upon sharp indentation with an AFM cantilever and quantifying their aptitude to sustain such a local shear strain. Beyond global mechanical paramet...

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Detalles Bibliográficos
Autores principales: Streppa, Laura, Ratti, Francesca, Goillot, Evelyne, Devin, Anne, Schaeffer, Laurent, Arneodo, Alain, Argoul, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988700/
https://www.ncbi.nlm.nih.gov/pubmed/29872100
http://dx.doi.org/10.1038/s41598-018-26797-4