NNMT activation can contribute to the development of fatty liver disease by modulating the NAD(+) metabolism

Nicotinamide N-methyltransferase (NNMT) catalyses the reaction between nicotinamide (NAM) and S-adenosylmethionine to produce 1-methylnicotinamide and S-adenosylhomocysteine. Recently, this enzyme has also been reported to modulate hepatic nutrient metabolism, but its role in the liver has not been...

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Detalles Bibliográficos
Autores principales: Komatsu, Motoaki, Kanda, Takeshi, Urai, Hidenori, Kurokochi, Arata, Kitahama, Rina, Shigaki, Shuhei, Ono, Takashi, Yukioka, Hideo, Hasegawa, Kazuhiro, Tokuyama, Hirobumi, Kawabe, Hiroshi, Wakino, Shu, Itoh, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988709/
https://www.ncbi.nlm.nih.gov/pubmed/29872122
http://dx.doi.org/10.1038/s41598-018-26882-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988709/
https://www.ncbi.nlm.nih.gov/pubmed/29872122
http://dx.doi.org/10.1038/s41598-018-26882-8

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