Molecular basis of resistance to the microtubule-depolymerizing antitumor compound plocabulin

Plocabulin (PM060184) is a microtubule depolymerizing agent with potent antiproliferative activity undergoing phase II clinical trials for the treatment of solid tumors. Plocabulin shows antifungal activity virtually abolishing growth of the filamentous fungus Aspergillus nidulans. A. nidulans hypha...

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Detalles Bibliográficos
Autores principales: Pantazopoulou, Areti, Galmarini, Carlos María, Peñalva, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988728/
https://www.ncbi.nlm.nih.gov/pubmed/29872155
http://dx.doi.org/10.1038/s41598-018-26736-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988728/
https://www.ncbi.nlm.nih.gov/pubmed/29872155
http://dx.doi.org/10.1038/s41598-018-26736-3

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