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Molecular basis of resistance to the microtubule-depolymerizing antitumor compound plocabulin
Plocabulin (PM060184) is a microtubule depolymerizing agent with potent antiproliferative activity undergoing phase II clinical trials for the treatment of solid tumors. Plocabulin shows antifungal activity virtually abolishing growth of the filamentous fungus Aspergillus nidulans. A. nidulans hypha...
Autores principales: | Pantazopoulou, Areti, Galmarini, Carlos María, Peñalva, Miguel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988728/ https://www.ncbi.nlm.nih.gov/pubmed/29872155 http://dx.doi.org/10.1038/s41598-018-26736-3 |
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