Native electrospray mass spectrometry approaches to probe the interaction between zinc and an anti-angiogenic peptide from histidine-rich glycoprotein

Zinc modulates the biological function of histidine-rich glycoprotein (HRG) through binding to its His-rich region (HRR). The Zn(2+)-binding properties of a 35 amino-acid biologically-active peptide mimic of the HRR, HRGP330, were investigated using dissociative mass spectrometry approaches in addit...

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Detalles Bibliográficos
Autores principales: Martin, Esther M., Kondrat, Frances D. L., Stewart, Alan J., Scrivens, James H., Sadler, Peter J., Blindauer, Claudia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988744/
https://www.ncbi.nlm.nih.gov/pubmed/29872214
http://dx.doi.org/10.1038/s41598-018-26924-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988744/
https://www.ncbi.nlm.nih.gov/pubmed/29872214
http://dx.doi.org/10.1038/s41598-018-26924-1

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