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Native electrospray mass spectrometry approaches to probe the interaction between zinc and an anti-angiogenic peptide from histidine-rich glycoprotein
Zinc modulates the biological function of histidine-rich glycoprotein (HRG) through binding to its His-rich region (HRR). The Zn(2+)-binding properties of a 35 amino-acid biologically-active peptide mimic of the HRR, HRGP330, were investigated using dissociative mass spectrometry approaches in addit...
Autores principales: | Martin, Esther M., Kondrat, Frances D. L., Stewart, Alan J., Scrivens, James H., Sadler, Peter J., Blindauer, Claudia A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988744/ https://www.ncbi.nlm.nih.gov/pubmed/29872214 http://dx.doi.org/10.1038/s41598-018-26924-1 |
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