Pathogenesis of cardiac ischemia reperfusion injury is associated with CK2α-disturbed mitochondrial homeostasis via suppression of FUNDC1-related mitophagy

Disturbed mitochondrial homeostasis contributes to the pathogenesis of cardiac ischemia reperfusion (IR) injury, although the underlying mechanism remains elusive. Here, we demonstrated that casein kinase 2α (CK2α) was upregulated following acute cardiac IR injury. Increased CK2α was shown to be ins...

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Detalles Bibliográficos
Autores principales: Zhou, Hao, Zhu, Pingjun, Wang, Jin, Zhu, Hong, Ren, Jun, Chen, Yundai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988750/
https://www.ncbi.nlm.nih.gov/pubmed/29540794
http://dx.doi.org/10.1038/s41418-018-0086-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988750/
https://www.ncbi.nlm.nih.gov/pubmed/29540794
http://dx.doi.org/10.1038/s41418-018-0086-7

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