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First characterization of a microsporidial triosephosphate isomerase and the biochemical mechanisms of its inactivation to propose a new druggable target

The microsporidia are a large group of intracellular parasites with a broad range of hosts, including humans. Encephalitozoon intestinalis is the second microsporidia species most frequently associated with gastrointestinal disease in humans, especially immunocompromised or immunosuppressed individu...

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Detalles Bibliográficos
Autores principales: García-Torres, Itzhel, De la Mora-De la Mora, Ignacio, Hernández-Alcántara, Gloria, Molina-Ortiz, Dora, Caballero-Salazar, Silvia, Olivos-García, Alfonso, Nava, Gabriela, López-Velázquez, Gabriel, Enríquez-Flores, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988755/
https://www.ncbi.nlm.nih.gov/pubmed/29872223
http://dx.doi.org/10.1038/s41598-018-26845-z