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Selective inhibition of receptor activator of NF-κB ligand (RANKL) in hematopoietic cells improves outcome after experimental myocardial infarction

ABSTRACT: The RANK (receptor activator of nuclear factor κB)/RANKL (RANK ligand)/OPG (osteoprotegerin) axis is activated after myocardial infarction (MI), but its pathophysiological role is not well understood. Here, we investigated how global and cell compartment-selective inhibition of RANKL affec...

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Detalles Bibliográficos
Autores principales: Slavic, Svetlana, Andrukhova, Olena, Ford, Kristopher, Handschuh, Stephan, Latic, Nejla, Reichart, Ursula, Sasgary, Soleman, Bergow, Claudia, Hofbauer, Lorenz C., Kostenuik, Paul J., Erben, Reinhold G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988763/
https://www.ncbi.nlm.nih.gov/pubmed/29736604
http://dx.doi.org/10.1007/s00109-018-1641-x