HIV-1 inhibition in cells with CXCR4 mutant genome created by CRISPR-Cas9 and piggyBac recombinant technologies

The C-X-C chemokine receptor type 4 (CXCR4) is one of the major co-receptors for human immunodeficiency virus type 1 (HIV-1) entry and is considered an important therapeutic target. However, its function in maintaining the development of hematopoietic stem cells (HSC) makes it difficult to be used f...

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Detalles Bibliográficos
Autores principales: Liu, Shuai, Wang, Qiankun, Yu, Xiao, Li, Yilin, Guo, Yandan, Liu, Zhepeng, Sun, Fuyun, Hou, Wei, Li, Chunmei, Wu, Li, Guo, Deyin, Chen, Shuliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988798/
https://www.ncbi.nlm.nih.gov/pubmed/29872154
http://dx.doi.org/10.1038/s41598-018-26894-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988798/
https://www.ncbi.nlm.nih.gov/pubmed/29872154
http://dx.doi.org/10.1038/s41598-018-26894-4

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