Phase I study of nab-paclitaxel, gemcitabine, and bevacizumab in patients with advanced cancers

BACKGROUND: We performed a phase I modified 3 + 3 dose escalation study to evaluate the safety and activity of bevacizumab plus gemcitabine and nab-paclitaxel in patients with advanced solid tumours. METHODS: Patients were given fixed dose gemcitabine plus increasing doses of nab-paclitaxel and beva...

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Detalles Bibliográficos
Autores principales: Sen, Shiraj, Kato, Shumei, Agarwal, Rishi, Piha-Paul, Sarina, Hess, Kenneth, Karp, Daniel, Janku, Filip, Fu, Siqing, Naing, Aung, Pant, Shubham, Falchook, Gerald, Tang, Chad, Wu, Xifeng, Ye, Yuanqing, Tsimberidou, Apostolia, Subbiah, Vivek, Kurzrock, Razelle, Byers, Lauren, Westin, Shannon, Lim, JoAnn, Bean, Stacie, Bass, Allison, Nguyen, Ly, Meric-Bernstam, Funda, Hong, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988803/
https://www.ncbi.nlm.nih.gov/pubmed/29695765
http://dx.doi.org/10.1038/s41416-018-0068-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988803/
https://www.ncbi.nlm.nih.gov/pubmed/29695765
http://dx.doi.org/10.1038/s41416-018-0068-z

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