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Rapamycin attenuates pathological hypertrophy caused by an absence of trabecular formation

Cardiac trabeculae are mesh-like muscular structures within ventricular walls. Subtle perturbations in trabeculation are associated with many congenital heart diseases (CHDs), and complete failure to form trabeculae leads to embryonic lethality. Despite the severe consequence of an absence of trabec...

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Detalles Bibliográficos
Autores principales: Fleming, Nicole D., Samsa, Leigh A., Hassel, David, Qian, Li, Liu, Jiandong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988815/
https://www.ncbi.nlm.nih.gov/pubmed/29872120
http://dx.doi.org/10.1038/s41598-018-26843-1