Genome-Wide Analysis of Interchromosomal Interaction Probabilities Reveals Chained Translocations and Overrepresentation of Translocation Breakpoints in Genes in a Cutaneous T-Cell Lymphoma Cell Line

In classical models of tumorigenesis, the accumulation of tumor promoting chromosomal aberrations is described as a gradual process. Next-generation sequencing-based methods have recently revealed complex patterns of chromosomal aberrations, which are beyond explanation by these classical models of...

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Detalles Bibliográficos
Autores principales: Steininger, Anne, Ebert, Grit, Becker, Benjamin V., Assaf, Chalid, Möbs, Markus, Schmidt, Christian A., Grabarczyk, Piotr, Jensen, Lars R., Przybylski, Grzegorz K., Port, Matthias, Kuss, Andreas W., Ullmann, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988852/
https://www.ncbi.nlm.nih.gov/pubmed/29900125
http://dx.doi.org/10.3389/fonc.2018.00183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988852/
https://www.ncbi.nlm.nih.gov/pubmed/29900125
http://dx.doi.org/10.3389/fonc.2018.00183

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