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Early Gray Matter Volume Loss in MAPT H1H1 de Novo PD Patients: A Possible Association With Cognitive Decline

The MAPT H1 haplotype has been identified as a predictor of cognitive decline in Parkinson's disease (PD). However, its underlying pathological mechanisms have not been fully established. In this work, using a cohort of 120 de novo PD patients with preserved cognition from the Parkinson's...

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Detalles Bibliográficos
Autores principales: Sampedro, Frederic, Marín-Lahoz, Juan, Martínez-Horta, Saul, Pagonabarraga, Javier, Kulisevsky, Jaime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989044/
https://www.ncbi.nlm.nih.gov/pubmed/29899731
http://dx.doi.org/10.3389/fneur.2018.00394