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Intermittent Hypoxia and Hypercapnia, a Hallmark of Obstructive Sleep Apnea, Alters the Gut Microbiome and Metabolome

Obstructive sleep apnea (OSA) is a common disorder characterized by episodic obstruction to breathing due to upper airway collapse during sleep. Because of the episodic airway obstruction, intermittently low O(2) (hypoxia) and high CO(2) (hypercapnia) ensue. OSA has been associated with adverse card...

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Detalles Bibliográficos
Autores principales: Tripathi, Anupriya, Melnik, Alexey V., Xue, Jin, Poulsen, Orit, Meehan, Michael J., Humphrey, Gregory, Jiang, Lingjing, Ackermann, Gail, McDonald, Daniel, Zhou, Dan, Knight, Rob, Dorrestein, Pieter C., Haddad, Gabriel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989129/
https://www.ncbi.nlm.nih.gov/pubmed/29896566
http://dx.doi.org/10.1128/mSystems.00020-18