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Intermittent Hypoxia and Hypercapnia, a Hallmark of Obstructive Sleep Apnea, Alters the Gut Microbiome and Metabolome
Obstructive sleep apnea (OSA) is a common disorder characterized by episodic obstruction to breathing due to upper airway collapse during sleep. Because of the episodic airway obstruction, intermittently low O(2) (hypoxia) and high CO(2) (hypercapnia) ensue. OSA has been associated with adverse card...
Autores principales: | Tripathi, Anupriya, Melnik, Alexey V., Xue, Jin, Poulsen, Orit, Meehan, Michael J., Humphrey, Gregory, Jiang, Lingjing, Ackermann, Gail, McDonald, Daniel, Zhou, Dan, Knight, Rob, Dorrestein, Pieter C., Haddad, Gabriel G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989129/ https://www.ncbi.nlm.nih.gov/pubmed/29896566 http://dx.doi.org/10.1128/mSystems.00020-18 |
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