Cargando…

Lobohedleolide suppresses hepatitis C virus replication via JNK/c-Jun-C/EBP-mediated down-regulation of cyclooxygenase-2 expression

Hepatitis C virus (HCV) chronically infects 2–3% people of the global population, which leads to liver cirrhosis and hepatocellular carcinoma. Drug resistance remains a serious problem that limits the effectiveness of US Food and Drug Administration (FDA)-approved direct-acting antiviral (DAA) drugs...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Chun-Kuang, Tseng, Chin-Kai, Liaw, Chih-Chuang, Huang, Chiung-Yao, Wei, Chih-Ku, Sheu, Jyh-Horng, Lee, Jin-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989199/
https://www.ncbi.nlm.nih.gov/pubmed/29875371
http://dx.doi.org/10.1038/s41598-018-26999-w