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Vms1p is a release factor for the ribosome-associated quality control complex

Eukaryotic cells employ the ribosome-associated quality control complex (RQC) to maintain homeostasis despite defects that cause ribosomes to stall. The RQC comprises the E3 ubiquitin ligase Ltn1p, the ATPase Cdc48p, Rqc1p, and Rqc2p. Upon ribosome stalling and splitting, the RQC assembles on the 60...

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Detalles Bibliográficos
Autores principales: Zurita Rendón, Olga, Fredrickson, Eric K., Howard, Conor J., Van Vranken, Jonathan, Fogarty, Sarah, Tolley, Neal D., Kalia, Raghav, Osuna, Beatriz A., Shen, Peter S., Hill, Christopher P., Frost, Adam, Rutter, Jared
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989216/
https://www.ncbi.nlm.nih.gov/pubmed/29875445
http://dx.doi.org/10.1038/s41467-018-04564-3