Glucose challenge metabolomics implicates medium-chain acylcarnitines in insulin resistance

Insulin resistance (IR) predisposes to type 2 diabetes and cardiovascular disease but its causes are incompletely understood. Metabolic challenges like the oral glucose tolerance test (OGTT) can reveal pathogenic mechanisms. We aimed to discover associations of IR with metabolite trajectories during...

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Detalles Bibliográficos
Autores principales: Nowak, Christoph, Hetty, Susanne, Salihovic, Samira, Castillejo-Lopez, Casimiro, Ganna, Andrea, Cook, Naomi L., Broeckling, Corey D., Prenni, Jessica E., Shen, Xia, Giedraitis, Vilmantas, Ärnlöv, Johan, Lind, Lars, Berne, Christian, Sundström, Johan, Fall, Tove, Ingelsson, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989236/
https://www.ncbi.nlm.nih.gov/pubmed/29875472
http://dx.doi.org/10.1038/s41598-018-26701-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989236/
https://www.ncbi.nlm.nih.gov/pubmed/29875472
http://dx.doi.org/10.1038/s41598-018-26701-0

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