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Pharmacokinetic Interaction Study of Ketamine and Rhynchophylline in Rat Plasma by Ultra-Performance Liquid Chromatography Tandem Mass Spectrometry

Eighteen Sprague-Dawley rats were randomly divided into three groups: ketamine group, rhynchophylline group, and ketamine combined with rhynchophylline group (n = 6). The rats of two groups received a single intraperitoneal administration of 30 mg/kg ketamine and 30 mg/kg rhynchophylline, respective...

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Detalles Bibliográficos
Autores principales: Chen, Lianguo, You, Weiwei, Chen, Dingwen, Cai, Yuan, Wang, Xianqin, Wen, Congcong, Wu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989277/
https://www.ncbi.nlm.nih.gov/pubmed/29951541
http://dx.doi.org/10.1155/2018/6562309