Cargando…
A single injection of crystallizable fragment domain–modified antibodies elicits durable protection from SHIV infection
In the absence of an effective and safe vaccine against HIV-1, the administration of broadly neutralizing antibodies (bNAbs) represents a logical alternative approach to prevent virus transmission. Here, we introduced two mutations encoding amino acid substitutions (M428L and N434S, collectively ref...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989326/ https://www.ncbi.nlm.nih.gov/pubmed/29662199 http://dx.doi.org/10.1038/s41591-018-0001-2 |