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Zika vaccines and therapeutics: landscape analysis and challenges ahead

BACKGROUND: Various Zika virus (ZIKV) vaccine candidates are currently in development. Nevertheless, unique challenges in clinical development and regulatory pathways may hinder the licensure of high-quality, safe, and effective ZIKV vaccines. DISCUSSION: Implementing phase 3 efficacy trials will be...

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Detalles Bibliográficos
Autores principales: Wilder-Smith, Annelies, Vannice, Kirsten, Durbin, Anna, Hombach, Joachim, Thomas, Stephen J., Thevarjan, Irani, Simmons, Cameron P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989336/
https://www.ncbi.nlm.nih.gov/pubmed/29871628
http://dx.doi.org/10.1186/s12916-018-1067-x