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A candidate gene identification strategy utilizing mouse to human big-data mining: “3R-tenet” in COPD genetic research
BACKGROUND: Early life impairments leading to lower lung function by adulthood are considered as risk factors for chronic obstructive pulmonary disease (COPD). Recently, we compared the lung transcriptomic profile between two mouse strains with extreme total lung capacities to identify plausible pul...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989378/ https://www.ncbi.nlm.nih.gov/pubmed/29871630 http://dx.doi.org/10.1186/s12931-018-0795-y |