A candidate gene identification strategy utilizing mouse to human big-data mining: “3R-tenet” in COPD genetic research

BACKGROUND: Early life impairments leading to lower lung function by adulthood are considered as risk factors for chronic obstructive pulmonary disease (COPD). Recently, we compared the lung transcriptomic profile between two mouse strains with extreme total lung capacities to identify plausible pul...

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Detalles Bibliográficos
Autores principales: Vishweswaraiah, Sangeetha, George, Leema, Purushothaman, Natarajan, Ganguly, Koustav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989378/
https://www.ncbi.nlm.nih.gov/pubmed/29871630
http://dx.doi.org/10.1186/s12931-018-0795-y

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