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Hemophagocytic lymphohistiocytosis with immunotherapy: brief review and case report

BACKGROUND: Hemophagocytic Lymphohistiocytosis (HLH), a rare but potentially fatal syndrome of immune hyperactivation, may be an under-recognized immune-related adverse event (irAE). Unlike other irAEs, HLH triggered by immune checkpoint blockade is not well described; no particular diagnostic guide...

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Detalles Bibliográficos
Autores principales: Sadaat, Masood, Jang, Sekwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989389/
https://www.ncbi.nlm.nih.gov/pubmed/29871698
http://dx.doi.org/10.1186/s40425-018-0365-3