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Assembly of highly repetitive genomes using short reads: the genome of discrete typing unit III Trypanosoma cruzi strain 231

Next-generation sequencing (NGS) methods are low-cost high-throughput technologies that produce thousands to millions of sequence reads. Despite the high number of raw sequence reads, their short length, relative to Sanger, PacBio or Nanopore reads, complicates the assembly of genomic repeats. Many...

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Detalles Bibliográficos
Autores principales: Baptista, Rodrigo P., Reis-Cunha, Joao Luis, DeBarry, Jeremy D., Chiari, Egler, Kissinger, Jessica C., Bartholomeu, Daniella C., Macedo, Andrea M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989580/
https://www.ncbi.nlm.nih.gov/pubmed/29442617
http://dx.doi.org/10.1099/mgen.0.000156