INK4a/ARF Expression Impairs Neurogenesis in the Brain of Irradiated Mice

Brain neurogenesis is severely impaired following exposure to ionizing radiation (IR). We and others have shown that the expression of the tumor suppressor gene p16INK4a is increased in tissues exposed to IR and thus hypothesized that its expression could limit neurogenesis in the irradiated brain....

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Detalles Bibliográficos
Autores principales: Le, Oanh, Palacio, Lina, Bernier, Gilbert, Batinic-Haberle, Ines, Hickson, Gilles, Beauséjour, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989693/
https://www.ncbi.nlm.nih.gov/pubmed/29706499
http://dx.doi.org/10.1016/j.stemcr.2018.03.025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989693/
https://www.ncbi.nlm.nih.gov/pubmed/29706499
http://dx.doi.org/10.1016/j.stemcr.2018.03.025

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