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INK4a/ARF Expression Impairs Neurogenesis in the Brain of Irradiated Mice
Brain neurogenesis is severely impaired following exposure to ionizing radiation (IR). We and others have shown that the expression of the tumor suppressor gene p16INK4a is increased in tissues exposed to IR and thus hypothesized that its expression could limit neurogenesis in the irradiated brain....
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989693/ https://www.ncbi.nlm.nih.gov/pubmed/29706499 http://dx.doi.org/10.1016/j.stemcr.2018.03.025 |