Noise in the Vertebrate Segmentation Clock Is Boosted by Time Delays but Tamed by Notch Signaling

Taming cell-to-cell variability in gene expression is critical for precise pattern formation during embryonic development. To investigate the source and buffering mechanism of expression variability, we studied a biological clock, the vertebrate segmentation clock, controlling the precise spatiotemp...

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Detalles Bibliográficos
Autores principales: Keskin, Sevdenur, Devakanmalai, Gnanapackiam S., Kwon, Soo Bin, Vu, Ha T., Hong, Qiyuan, Lee, Yin Yeng, Soltani, Mohammad, Singh, Abhyudai, Ay, Ahmet, Özbudak, Ertuğrul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989725/
https://www.ncbi.nlm.nih.gov/pubmed/29768214
http://dx.doi.org/10.1016/j.celrep.2018.04.069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989725/
https://www.ncbi.nlm.nih.gov/pubmed/29768214
http://dx.doi.org/10.1016/j.celrep.2018.04.069

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