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eIF2β, a subunit of translation‐initiation factor EIF2, is a potential therapeutic target for non‐small cell lung cancer

To identify novel therapeutic targets for non‐small cell lung cancer (NSCLC), we conducted an integrative study in the following 3 stages: (i) identification of potential target gene(s) through shRNA functional screens in 2 independent NSCLC cell lines; (ii) validation of the clinical relevance of i...

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Detalles Bibliográficos
Autores principales: Tanaka, Ichidai, Sato, Mitsuo, Kato, Toshio, Goto, Daiki, Kakumu, Tomohiko, Miyazawa, Ayako, Yogo, Naoyuki, Hase, Tetsunari, Morise, Masahiro, Sekido, Yoshitaka, Girard, Luc, Minna, John D., Byers, Lauren A., Heymach, John V., Coombes, Kevin R., Kondo, Masashi, Hasegawa, Yoshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989750/
https://www.ncbi.nlm.nih.gov/pubmed/29624814
http://dx.doi.org/10.1111/cas.13602