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Aging related cognitive changes associated with Alzheimer's disease in Down syndrome

OBJECTIVE: Individuals with Down syndrome (DS) have an extremely high genetic risk for Alzheimer's disease (AD), however, the course of cognitive decline associated with progression to dementia is ill‐defined. Data‐driven methods can estimate long‐term trends from cross‐sectional data while adj...

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Detalles Bibliográficos
Autores principales: Firth, Nicholas C., Startin, Carla M., Hithersay, Rosalyn, Hamburg, Sarah, Wijeratne, Peter A., Mok, Kin Y., Hardy, John, Alexander, Daniel C., Strydom, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989753/
https://www.ncbi.nlm.nih.gov/pubmed/29928657
http://dx.doi.org/10.1002/acn3.571