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Preventing muscle wasting by osteoporosis drug alendronate in vitro and in myopathy models via sirtuin‐3 down‐regulation

BACKGROUND: A global consensus on the loss of skeletal muscle mass and function in humans refers as sarcopenia and cachexia including diabetes, obesity, renal failure, and osteoporosis. Despite a current improvement of sarcopenia or cachexia with exercise training and supportive therapies, alternati...

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Detalles Bibliográficos
Autores principales: Chiu, Hsien‐Chun, Chiu, Chen‐Yuan, Yang, Rong‐Sen, Chan, Ding‐Cheng, Liu, Shing‐Hwa, Chiang, Chih‐Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989760/
https://www.ncbi.nlm.nih.gov/pubmed/29512306
http://dx.doi.org/10.1002/jcsm.12289