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The safety, tolerability, and pharmacokinetic profile of GSK2838232, a novel 2nd generation HIV maturation inhibitor, as assessed in healthy subjects

This work aimed to assess the safety, tolerability, pharmacokinetics (PK), and relative bioavailability of GSK2838232, an investigational HIV maturation inhibitor. GSK2838232 was administered over four dose‐escalation studies in healthy subjects which assessed single oral doses (5‐250 mg) and repeat...

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Detalles Bibliográficos
Autores principales: Johnson, Mark, Jewell, Roxanne C., Peppercorn, Amanda, Gould, Elizabeth, Xu, Jianfeng, Lou, Yu, Davies, Matthew, Baldwin, Sandra, Tenorio, Allan R., Burke, Matthew, Jeffrey, Jerry, Johns, Brian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989765/
https://www.ncbi.nlm.nih.gov/pubmed/29930812
http://dx.doi.org/10.1002/prp2.408