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hmSOD1 gene mutation‐induced disturbance in iron metabolism is mediated by impairment of Akt signalling pathway

BACKGROUND: Recently, skeletal muscle atrophy, impairment of iron metabolism, and insulin signalling have been reported in rats suffering from amyotrophic lateral sclerosis (ALS). However, the interrelationship between these changes has not been studied. We hypothesize that an impaired Akt–FOXO3a si...

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Detalles Bibliográficos
Autores principales: Halon‐Golabek, Malgorzata, Borkowska, Andzelika, Kaczor, Jan J., Ziolkowski, Wieslaw, Flis, Damian J., Knap, Narcyz, Kasperuk, Kajetan, Antosiewicz, Jedrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989766/
https://www.ncbi.nlm.nih.gov/pubmed/29380557
http://dx.doi.org/10.1002/jcsm.12283