A novel nitroreductase-enhanced MRI contrast agent and its potential application in bacterial imaging

Nitroreductases (NTRs) are known to be able to metabolize nitro-substituted compounds in the presence of reduced nicotinamide adenine dinucleotide (NADH) as an electron donor. NTRs are present in a wide range of bacterial genera and, to a lesser extent, in eukaryotes hypoxic tumour cells and tumorou...

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Detalles Bibliográficos
Autores principales: Liu, Yun, Zhang, Leilei, Nazare, Marc, Yao, Qingqiang, Hu, Hai-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989822/
https://www.ncbi.nlm.nih.gov/pubmed/29881679
http://dx.doi.org/10.1016/j.apsb.2017.11.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989822/
https://www.ncbi.nlm.nih.gov/pubmed/29881679
http://dx.doi.org/10.1016/j.apsb.2017.11.001

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