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Molecular pathogenesis of pancreatic ductal adenocarcinoma: Impact of passenger strand of pre‐miR‐148a on gene regulation

We previously used RNA sequencing to establish the microRNA (miRNA) expression signature of pancreatic ductal adenocarcinoma (PDAC). We found that both strands of pre‐miR‐148a (miR‐148a‐5p: the passenger strand and miR‐148a‐3p: the guide strand) were downregulated in cancer tissues. Ectopic expressi...

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Detalles Bibliográficos
Autores principales: Idichi, Tetsuya, Seki, Naohiko, Kurahara, Hiroshi, Fukuhisa, Haruhi, Toda, Hiroko, Shimonosono, Masataka, Okato, Atsushi, Arai, Takayuki, Kita, Yoshiaki, Mataki, Yuko, kijima, Yuko, Maemura, Kosei, Natsugoe, Shoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989856/
https://www.ncbi.nlm.nih.gov/pubmed/29660218
http://dx.doi.org/10.1111/cas.13610